Document Type : Scientific extension

Author

Assistant Professor . Aerospace Research Institute, Ministry of Science, Research and Technology, Tehran, Iran.

Abstract

Microgravity and cosmic radiation are the space environmental stresses which can cause DNA damage in living organisms. Radiations injuries the cell DNA directly through the interaction of charged particles with DNA molecules or indirectly by the production of free radicals. In addition, radiation can alter cell wall composition, activate free radical scavenging enzymes, and accumulate antioxidant compounds. Although plants have evolved some mechanisms to deal with the damages, space conditions, especially microgravity can play a role in repairing DNA damage. More DNA damages can induce double strand breaks of DNA, chromosome abnormality, micro-nuclei formation, and increase the risk of cell death. In this study, the effect of space environmental stresses on DNA damage and response mechanisms will be investigated in space flight or simulated conditions.

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Main Subjects

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