Document Type : Scientific extension

Authors

1 M.Sc.Faculty of Materials & Manufacturing Technologies, Malek Ashtar University of Technology, Tehran, Iran.

2 Associate Professor .Faculty of Materials & Manufacturing Technologies, Malek Ashtar University of Technology,, Tehran, Iran.

3 Ph.D. Student. Faculty of Materials & Manufacturing Technologies, Malek Ashtar University of Technology, Tehran, Iran.

4 Professor, Faculty of Materials & Manufacturing Technologies, Malek Ashtar University of Technology,Tehran, Iran.

5 PhD Student . Department of Aerospace Engineering, Ferdowsi University of Mashhad . Mashhad, Iran.

Abstract

Microgravity and cosmic radiation are the space environmental stresses which can cause DNA damage in living organisms. Radiations injurie the cell DNA directly through the interaction of charged particles with DNA molecules or indirectly by the production of free radicals. In addition, radiation can alter cell wall composition, activate free radical scavenging enzymes, and accumulate antioxidant compounds. Although plants have evolved some mechanisms to deal with the damages, space conditions, especially microgravity can play a role in repairing DNA damage. More DNA damages can induce double strands breaks of DNA, chromosome abnormality, micro-nuclei formation, and increase the risk of cell death. In this study, effect of space environmental stresses on DNA damage and response mechanisms will be investigated in space flight or simulated conditions.

Keywords

Main Subjects

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