Document Type : Scientific extension


Assistant Professor، Aerospace Research Institute, Ministry of Science, Research and Technology, Tehran, Iran


Along with the advancement of space science and efforts to extend life beyond the earth, it is important to ‎study the response of microorganisms to microgravity conditions, because the microorganisms will unavoidably ‎be sent to space together with the equipment and passengers. Indeed, exposure to stressful space conditions ‎maybe activates some microorganisms' defense mechanisms which can increase their pathogenicity. Until now, ‎only the responses of a few typical microbes to microgravity have been investigated and the completion of these ‎studies has been delayed due to technical problems and high costs, but it is necessary to study host-microbial ‎interactions, in order to predict these behaviors and take precautionary measures during space flight and even ‎during space station deployment. In the present study, we will review some microbial changes such as growth ‎and metabolic changes and alterations in the expression of genes and proteins under the physical stress of space ‎flight and microgravity simulators.‎


Main Subjects

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