بررسی مدل های کشت سلول گیاهی برای تحقیقات فضایی

حسن پور, حلیمه

doi:10.30699/jtae.2023.7.1.2

نوع مقاله : علمی- ترویجی

نویسنده

حلیمه حسن پور

استادیار، پژوهشگاه هوافضا، وزارت علوم، تحقیقات و فناوری، تهران، ایران

https://doi.org/10.30699/jtae.2023.7.1.2

چکیده

انتخاب نمونه مناسب زیستی برای مطالعات فضایی از اهمیت بسزایی برخوردار است. کشت سوسپانسیون سلول های گیاهی بدلیل دارا بودن جمعیت یکنواخت از سلول‌های در حال تکثیر، شرایط مناسبی را برای مطالعه انواع تنش‌ها از جمله میکروگراویتی فراهم می نمایند. سیستم‌های کشت سلولی در آزمایشگاه می‌تواند به صورت مدل های کشت دو بعدی و سه بعدی انجام شود. در مدل دو بعدی سلول‌ها بصورت تک لایه کشت شده و پاسخ های رشد و تمایز متفاوتی را با شرایط طبیعی نشان می‌دهند. درحالیکه، سلول‌ها در کشت سه بعدی در شرایطی کشت می شوند که مشابه با شرایط طبیعی سلول و بافت در بدن موجود زنده بوده و برای اهداف دارویی، تولید متابولیت های ثانویه و بیومس در مقیاس بالا کاربرد دارد. در این پژوهش، پیشرفت های اخیر و تکنولوژی‌های مورد استفاده برای کشت سه بعدی سلول مورد مطالعه قرار خواهد گرفت.

کلیدواژه‌ها

موضوعات

علوم زیستی/محیط زیست/فیزیولوژی گیاهی/ فیزیولوژی جانوری/سنجش از دور/...

عنوان مقاله [English]

Investigation of plant cell culture models for space studies

نویسنده [English]

Halimeh Hassanpour

Assistant Professor, Faculty Aerospace Research Institute, Ministry of Science, Research and Technology, Tehran, Iran

چکیده [English]

The selection of suitable biological sample for space studies has vital importance. Plant cell suspension culture containing a homogenous population of proliferating cells prepares the proper situation to study various cell responses under stress conditions, especially microgravity. Cell culture systems in the laboratory can be performed in the two-dimensional (2D) and 3D culture models. In the 2D culture model, cells are cultured as a monolayer and show different growth and differentiation responses compared to normal conditions. While in the 2D model, cells are cultured in conditions that are similar to the normal conditions of cells and tissues in the living organisms and are used for medicinal purposes, production of secondary metabolites and biomass on a large scale. In this research, recent advancements and technologies used for 3D cell culture will be studied.

کلیدواژه‌ها [English]

3D cell culture
Bioreactor
Scaffold
Pharmaceutical metabolites

مراجع

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فناوری در مهندسی هوافضا

بررسی مدل های کشت سلول گیاهی برای تحقیقات فضایی

مراجع

مراجع

دوره 7، شماره 1 - شماره پیاپی 24
اردیبهشت 1402
صفحه 17-23

بررسی مدل های کشت سلول گیاهی برای تحقیقات فضایی

مراجع

مراجع

دوره 7، شماره 1 - شماره پیاپی 24اردیبهشت 1402صفحه 17-23

دوره 7، شماره 1 - شماره پیاپی 24
اردیبهشت 1402
صفحه 17-23